Abstract Cyclin dependent kinases (CDKs) are serine/threonine kinases that are proposed as promising candidate targets for cancer treatment.These proteins complexed with cyclins play a critical role in cell cycle progression.Most CDKs demonstrate substantially higher expression in cancer tissues compared with normal tissues and, DEEP IMMUNE LICORIC

Lifelong learning through continuing professional development (CPD) and medical education is critical for healthcare professionals to stay abreast of knowledge and skills and provide an optimal standard of care to patients.In Europe, CPD and medical education are fragmented as there are numerous models, providers and national regulations and a lack

Reduced levels of brain-derived neurotrophic factor DETOXIFYING MASQUE (BDNF) are thought to contribute to the pathophysiology of Rett syndrome (RTT), a severe neurodevelopmental disorder caused by loss-of-function mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2).In Mecp2 mutant mice, BDNF deficits have been associated with breat